Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway

Folic acid- (FA-) induced kidney injury is characterized by the tubule damage due to the disturbance of the antioxidant system and subsequent interstitial fibrosis. FG-4592 is an inhibitor of prolyl hydroxylase of hypoxia-inducible factor (HIF), an antioxidant factor. The present study investigated...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xue, Zou, Yu, Xing, Jia, Fu, Yuan-Yuan, Wang, Kai-Yue, Wan, Peng-Zhi, Zhai, Xiao-Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995323/
https://www.ncbi.nlm.nih.gov/pubmed/32051732
http://dx.doi.org/10.1155/2020/6286984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995323/
https://www.ncbi.nlm.nih.gov/pubmed/32051732
http://dx.doi.org/10.1155/2020/6286984

Ejemplares similares