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The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
Metabolic remodeling is a key phenomenon in the occurrence and development of tumors. It not only offers materials and energy for the survival and proliferation of tumor cells, but also protects tumor cells so that they may survive, proliferate and transfer in the harsh microenvironment. This paper...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995370/ https://www.ncbi.nlm.nih.gov/pubmed/32047547 http://dx.doi.org/10.7150/jca.31406 |
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author | Chang, Ligong Fang, Surong Gu, Wei |
author_facet | Chang, Ligong Fang, Surong Gu, Wei |
author_sort | Chang, Ligong |
collection | PubMed |
description | Metabolic remodeling is a key phenomenon in the occurrence and development of tumors. It not only offers materials and energy for the survival and proliferation of tumor cells, but also protects tumor cells so that they may survive, proliferate and transfer in the harsh microenvironment. This paper attempts to reveal the role of abnormal metabolism in the development of lung cancer by considering the processes of glycolysis and lipid metabolism, Identification of the molecules that are specifically used in the processes of glycolysis and lipid metabolism, and their underlying molecular mechanisms, is of great clinical and theoretical significance. We will focus on the recent progress in elucidating the molecular mechanism of metabolic remodeling in lung cancer. |
format | Online Article Text |
id | pubmed-6995370 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-69953702020-02-11 The Molecular Mechanism of Metabolic Remodeling in Lung Cancer Chang, Ligong Fang, Surong Gu, Wei J Cancer Review Metabolic remodeling is a key phenomenon in the occurrence and development of tumors. It not only offers materials and energy for the survival and proliferation of tumor cells, but also protects tumor cells so that they may survive, proliferate and transfer in the harsh microenvironment. This paper attempts to reveal the role of abnormal metabolism in the development of lung cancer by considering the processes of glycolysis and lipid metabolism, Identification of the molecules that are specifically used in the processes of glycolysis and lipid metabolism, and their underlying molecular mechanisms, is of great clinical and theoretical significance. We will focus on the recent progress in elucidating the molecular mechanism of metabolic remodeling in lung cancer. Ivyspring International Publisher 2020-01-13 /pmc/articles/PMC6995370/ /pubmed/32047547 http://dx.doi.org/10.7150/jca.31406 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Review Chang, Ligong Fang, Surong Gu, Wei The Molecular Mechanism of Metabolic Remodeling in Lung Cancer |
title | The Molecular Mechanism of Metabolic Remodeling in Lung Cancer |
title_full | The Molecular Mechanism of Metabolic Remodeling in Lung Cancer |
title_fullStr | The Molecular Mechanism of Metabolic Remodeling in Lung Cancer |
title_full_unstemmed | The Molecular Mechanism of Metabolic Remodeling in Lung Cancer |
title_short | The Molecular Mechanism of Metabolic Remodeling in Lung Cancer |
title_sort | molecular mechanism of metabolic remodeling in lung cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995370/ https://www.ncbi.nlm.nih.gov/pubmed/32047547 http://dx.doi.org/10.7150/jca.31406 |
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