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The Molecular Mechanism of Metabolic Remodeling in Lung Cancer

Metabolic remodeling is a key phenomenon in the occurrence and development of tumors. It not only offers materials and energy for the survival and proliferation of tumor cells, but also protects tumor cells so that they may survive, proliferate and transfer in the harsh microenvironment. This paper...

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Detalles Bibliográficos
Autores principales: Chang, Ligong, Fang, Surong, Gu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995370/
https://www.ncbi.nlm.nih.gov/pubmed/32047547
http://dx.doi.org/10.7150/jca.31406
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author Chang, Ligong
Fang, Surong
Gu, Wei
author_facet Chang, Ligong
Fang, Surong
Gu, Wei
author_sort Chang, Ligong
collection PubMed
description Metabolic remodeling is a key phenomenon in the occurrence and development of tumors. It not only offers materials and energy for the survival and proliferation of tumor cells, but also protects tumor cells so that they may survive, proliferate and transfer in the harsh microenvironment. This paper attempts to reveal the role of abnormal metabolism in the development of lung cancer by considering the processes of glycolysis and lipid metabolism, Identification of the molecules that are specifically used in the processes of glycolysis and lipid metabolism, and their underlying molecular mechanisms, is of great clinical and theoretical significance. We will focus on the recent progress in elucidating the molecular mechanism of metabolic remodeling in lung cancer.
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spelling pubmed-69953702020-02-11 The Molecular Mechanism of Metabolic Remodeling in Lung Cancer Chang, Ligong Fang, Surong Gu, Wei J Cancer Review Metabolic remodeling is a key phenomenon in the occurrence and development of tumors. It not only offers materials and energy for the survival and proliferation of tumor cells, but also protects tumor cells so that they may survive, proliferate and transfer in the harsh microenvironment. This paper attempts to reveal the role of abnormal metabolism in the development of lung cancer by considering the processes of glycolysis and lipid metabolism, Identification of the molecules that are specifically used in the processes of glycolysis and lipid metabolism, and their underlying molecular mechanisms, is of great clinical and theoretical significance. We will focus on the recent progress in elucidating the molecular mechanism of metabolic remodeling in lung cancer. Ivyspring International Publisher 2020-01-13 /pmc/articles/PMC6995370/ /pubmed/32047547 http://dx.doi.org/10.7150/jca.31406 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Chang, Ligong
Fang, Surong
Gu, Wei
The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
title The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
title_full The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
title_fullStr The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
title_full_unstemmed The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
title_short The Molecular Mechanism of Metabolic Remodeling in Lung Cancer
title_sort molecular mechanism of metabolic remodeling in lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995370/
https://www.ncbi.nlm.nih.gov/pubmed/32047547
http://dx.doi.org/10.7150/jca.31406
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