p16 promotes proliferation in cervical carcinoma cells through CDK6-HuR-IL1A axis

The Cyclin-Dependent Kinase Inhibitor p16 (p16) acts as a tumor suppressor in most cells, but for HPV transformed cervical cancer, in which oncoprotein E7 expressed by human papillomavirus (HPV) mediates the degradation of retinoblastoma protein (Rb), p16 exhibits oncogenic activity. Our study was c...

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Detalles Bibliográficos
Autores principales: Li, Mingzhe, Yang, Jiong, Liu, Kaiyu, Yang, Jianming, Zhan, Xiangwen, Wang, Le, Shen, Xiaomeng, Chen, Jing, Mao, Zebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995400/
https://www.ncbi.nlm.nih.gov/pubmed/32047552
http://dx.doi.org/10.7150/jca.35479

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