Insulin-Like Growth Factor Binding Protein-Related Protein 1 Activates Primary Hepatic Stellate Cells via Autophagy Regulated by the PI3K/Akt/mTOR Signaling Pathway

BACKGROUND: Autophagy is a self-degrading process. Previously, we showed that insulin-like growth factor binding protein-related protein 1 (IGFBPrP1) is a novel transforming growth factor β1 (TGFβ1)-interacting factor in liver fibrosis; the role of TGFβ1-mediated autophagy in hepatic stellate cells...

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Detalles Bibliográficos
Autores principales: Zhou, Yuzheng, Zhang, Qianqian, Kong, Yangyang, Guo, Xiaohong, Zhang, Haiyan, Fan, Huiqin, Liu, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995450/
https://www.ncbi.nlm.nih.gov/pubmed/31468266
http://dx.doi.org/10.1007/s10620-019-05798-x

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