Long-Lasting Effects of GSPE on Ileal GLP-1R Gene Expression Are Associated with a Hypomethylation of the GLP-1R Promoter in Female Wistar Rats

Flavonoids have been shown to modulate GLP-1 in obesity. GLP-1 induces some of its effects through the intestinal GLP-1 receptor (GLP-1R), though no data exist on how flavonoids affect this receptor. Here, we examine how a dose of grape seed proanthocyanidin extract (GSPE) with anti-obesity activity...

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Detalles Bibliográficos
Autores principales: Ginés, Iris, Gil-Cardoso, Katherine, D’Addario, Claudio, Falconi, Anastasia, Bellia, Fabio, Blay, M Teresa, Terra, Ximena, Ardévol, Anna, Pinent, Montserrat, Beltrán-Debón, Raúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995503/
https://www.ncbi.nlm.nih.gov/pubmed/31842341
http://dx.doi.org/10.3390/biom9120865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995503/
https://www.ncbi.nlm.nih.gov/pubmed/31842341
http://dx.doi.org/10.3390/biom9120865

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