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The Interplay between Retinal Pathways of Cholesterol Output and Its Effects on Mouse Retina
In mammalian retina, cholesterol excess is mainly metabolized to oxysterols by cytochromes P450 27A1 (CYP27A1) and 46A1 (CYP46A1) or removed on lipoprotein particles containing apolipoprotein E (APOE). In contrast, esterification by sterol-O-acyltransferase 1 (SOAT) plays only a minor role in this p...
Autores principales: | Petrov, Alexey M., Astafev, Artem A., Mast, Natalia, Saadane, Aicha, El-Darzi, Nicole, Pikuleva, Irina A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995521/ https://www.ncbi.nlm.nih.gov/pubmed/31842366 http://dx.doi.org/10.3390/biom9120867 |
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