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Activation of General Control Nonderepressible-2 Kinase Ameliorates Glucotoxicity in Human Peritoneal Mesothelial Cells, Preserves Their Integrity, and Prevents Mesothelial to Mesenchymal Transition

Along with infections, ultrafiltration failure due to the toxicity of glucose-containing peritoneal dialysis (PD) solutions is the Achilles’ heel of PD method. Triggered by the protective effect of general control nonderepressible-2 (GCN-2) kinase activation against high-glucose conditions in other...

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Detalles Bibliográficos
Autores principales:	Eleftheriadis, Theodoros, Pissas, Georgios, Antoniadi, Georgia, Nikolaou, Evdokia, Golfinopoulos, Spyridon, Liakopoulos, Vassilios, Stefanidis, Ioannis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995539/ https://www.ncbi.nlm.nih.gov/pubmed/31817562 http://dx.doi.org/10.3390/biom9120832

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