Evaluating Iso-Mukaadial Acetate and Ursolic Acid Acetate as Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase Inhibitors

To date, Plasmodium falciparum is one of the most lethal strains of the malaria parasite. P. falciparum lacks the required enzymes to create its own purines via the de novo pathway, thereby making Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase (PfHGXPT) a crucial enzym...

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Detalles Bibliográficos
Autores principales: Opoku, Francis, Govender, Penny P., Pooe, Ofentse J., Simelane, Mthokozisi B.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995562/
https://www.ncbi.nlm.nih.gov/pubmed/31835879
http://dx.doi.org/10.3390/biom9120861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995562/
https://www.ncbi.nlm.nih.gov/pubmed/31835879
http://dx.doi.org/10.3390/biom9120861

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