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Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren

Classical non-homologous end joining (NHEJ) is a molecular pathway that detects, processes, and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. Mutations in several NHEJ genes result in neurological abnormalities and immunodeficiency both in humans and mice. The NHEJ pathway is re...

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Detalles Bibliográficos
Autores principales:	Castañeda-Zegarra, Sergio, Huse, Camilla, Røsand, Øystein, Sarno, Antonio, Xing, Mengtan, Gago-Fuentes, Raquel, Zhang, Qindong, Alirezaylavasani, Amin, Werner, Julia, Ji, Ping, Liabakk, Nina-Beate, Wang, Wei, Bjørås, Magnar, Oksenych, Valentyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995585/ https://www.ncbi.nlm.nih.gov/pubmed/31795137 http://dx.doi.org/10.3390/biom9120798

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