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The Role of the Ω-Loop in Regulation of the Catalytic Activity of TEM-Type β-Lactamases

Bacterial resistance to β-lactams, the most commonly used class of antibiotics, poses a global challenge. This resistance is caused by the production of bacterial enzymes that are termed β-lactamases (βLs). The evolution of serine-class A β-lactamases from penicillin-binding proteins (PBPs) is relat...

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Detalles Bibliográficos
Autores principales:	Egorov, Alexey, Rubtsova, Maya, Grigorenko, Vitaly, Uporov, Igor, Veselovsky, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995641/ https://www.ncbi.nlm.nih.gov/pubmed/31835662 http://dx.doi.org/10.3390/biom9120854

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