Cargando…

Nucleolar and Spindle Associated Protein 1 (NUSAP1) Promotes Bladder Cancer Progression Through the TGF-β Signaling Pathway

PURPOSE: NUSAP1 has been reported to be involved in the progression of several types of cancer. However, its expression and exact role in bladder cancer (BLCA) remains elusive. The aim of this study was to determine the expression and role of NUSAP1 in BLCA. METHODS: Tissue microarray, real-time PCR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Shun, Yin, Hubin, Tong, Hang, Zhan, Kai, Yang, Guang, Hossain, Mohammad Arman, Li, Tinghao, Gou, Xin, He, Weiyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996025/ https://www.ncbi.nlm.nih.gov/pubmed/32099387 http://dx.doi.org/10.2147/OTT.S237127

Ejemplares similares

Nucleolar spindle associated protein 1 (NUSAP1) facilitates proliferation of hepatocellular carcinoma cells
por: Hou, Sinan, et al.
Publicado: (2019)

Distinct Mitotic Functions of Nucleolar and Spindle-Associated Protein 1 (NuSAP1) Are Controlled by Two Consensus SUMOylation Sites
por: Damizia, Michela, et al.
Publicado: (2023)

An epithelial–mesenchymal transition-related long noncoding RNA signature correlates with the prognosis and progression in patients with bladder cancer
por: Tong, Hang, et al.
Publicado: (2021)

C1QTNF6 Overexpression Acts as a Predictor of Poor Prognosis in Bladder Cancer Patients
por: Zhu, Xin, et al.
Publicado: (2020)

Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming
por: Li, Tinghao, et al.
Publicado: (2021)

Down-Regulation of Nucleolar and Spindle-Associated Protein 1 (NUSAP1) Expression Suppresses Tumor and Cell Proliferation and Enhances Anti-Tumor Effect of Paclitaxel in Oral Squamous Cell Carcinoma
por: Okamoto, Atsushi, et al.
Publicado: (2015)

YTHDF1 Promotes Bladder Cancer Cell Proliferation via the METTL3/YTHDF1–RPN2–PI3K/AKT/mTOR Axis
por: Zhu, Junlong, et al.
Publicado: (2023)

Nucleolar and Spindle Associated Protein 1 (NUSAP1) Inhibits Cell Proliferation and Enhances Susceptibility to Epirubicin In Invasive Breast Cancer Cells by Regulating Cyclin D Kinase (CDK1) and DLGAP5 Expression
por: Zhang, Xi, et al.
Publicado: (2018)

EGF-induced nuclear translocation of SHCBP1 promotes bladder cancer progression through inhibiting RACGAP1-mediated RAC1 inactivation
por: Yin, Hubin, et al.
Publicado: (2022)

NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization
por: Raemaekers, Tim, et al.
Publicado: (2003)

O-GlcNAcylation Enhances NUSAP1 Stability and Promotes Bladder Cancer Aggressiveness
por: Chen, Yifan, et al.
Publicado: (2021)

β-elemene enhances cisplatin-induced apoptosis in bladder cancer cells through the ROS-AMPK signaling pathway
por: Gan, Daoju, et al.
Publicado: (2020)

SPHK1 contributes to cisplatin resistance in bladder cancer cells via the NONO/STAT3 axis
por: Qin, Zijia, et al.
Publicado: (2021)

NUSAP1 promotes invasion and metastasis of prostate cancer
por: Gordon, Catherine A., et al.
Publicado: (2017)

Identification and clinical validation of NUSAP1 as a novel prognostic biomarker in ovarian cancer
por: Gou, Rui, et al.
Publicado: (2022)

Increased NUSAP1 expression is associated with lymph node metastasis and survival prognosis in bladder urothelial carcinoma
por: Hou, Jian, et al.
Publicado: (2022)

Identification of a 13-mRNA signature for predicting disease progression and prognosis in patients with bladder cancer
por: Yin, Hubin, et al.
Publicado: (2020)

A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer
por: Zhang, Chen, et al.
Publicado: (2020)

Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway
por: Wu, Xianqiu, et al.
Publicado: (2017)

MicroRNA‐769‐5p suppresses cell growth and migration via targeting NUSAP1 in bladder cancer
por: Chen, Yifan, et al.
Publicado: (2020)

NUSAP1 Promotes Gastric Cancer Tumorigenesis and Progression by Stabilizing the YAP1 Protein
por: Guo, Hui, et al.
Publicado: (2021)

Alternatively activated NUSAP1 promotes tumor growth and indicates poor prognosis in hepatocellular carcinoma
por: Shi, Chao, et al.
Publicado: (2019)

Expression Profile and Gene Regulation Network of NUSAP1 in Pan Cancers Based on Integrated Bioinformatics Analysis
por: Zhu, Xiaodi, et al.
Publicado: (2023)

Decreased Expression of NUSAP1 Predicts Poor Overall Survival in Cervical Cancer
por: Xie, Qiqi, et al.
Publicado: (2020)

MCM2 and NUSAP1 Are Potential Biomarkers for the Diagnosis and Prognosis of Pancreatic Cancer
por: Deng, Yajun, et al.
Publicado: (2020)

HMGB1-mediated autophagy attenuates gemcitabine-induced apoptosis in bladder cancer cells involving JNK and ERK activation
por: Yin, Hubin, et al.
Publicado: (2017)

Corrigendum: NUSAP1 Promotes Gastric Cancer Tumorigenesis and Progression by Stabilizing the YAP1 Protein
por: Guo, Hui, et al.
Publicado: (2021)

Downregulation of nucleolar and spindle-associated protein 1 expression suppresses liver cancer cell function
por: Wang, Yifan, et al.
Publicado: (2019)

NUSAP1 potentiates chemoresistance in glioblastoma through its SAP domain to stabilize ATR
por: Zhao, Yuzu, et al.
Publicado: (2020)

Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression
por: Zhang, Ling, et al.
Publicado: (2021)

NUSAP1 Could be a Potential Target for Preventing NAFLD Progression to Liver Cancer
por: Zeng, Taofei, et al.
Publicado: (2022)

Nucleolar and coiled-body phosphoprotein 1 (NOLC1) regulates the nucleolar retention of TRF2
por: Yuan, Fuwen, et al.
Publicado: (2017)

Nucleolar and spindle associated protein 1 promotes metastasis of cervical carcinoma cells by activating Wnt/β-catenin signaling
por: Li, Han, et al.
Publicado: (2019)

Prognostic significance of HER2 status evaluation using immunohistochemistry in patients with urothelial carcinoma of the bladder: A retrospective single‑center experience
por: Bai, Xuesong, et al.
Publicado: (2022)

Increased expression of NuSAP in recurrent prostate cancer is mediated by E2F1
por: Gulzar, Zulfiqar G, et al.
Publicado: (2012)

Analyzing Roles of NUSAP1 From Clinical, Molecular Mechanism and Immune Perspectives in Hepatocellular Carcinoma
por: Zhu, Wenjie, et al.
Publicado: (2021)

microRNA-569 inhibits tumor metastasis in pancreatic cancer by directly targeting NUSAP1
por: Guo, Xiaohui, et al.
Publicado: (2022)

NUSAP1, a novel stemness‐related protein, promotes early recurrence of hepatocellular carcinoma
por: Li, Jinying, et al.
Publicado: (2022)

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability
por: Hussain, Shobbir, et al.
Publicado: (2009)

RNA-Binding Protein COL14A1, TNS1, NUSAP1 and YWHAE Are Valid Biomarkers to Predict Peritoneal Metastasis in Gastric Cancer
por: Jiang, Yue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2n0jae31fk953g9j4f52v5b19d