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Bile acid receptor agonists in primary biliary cholangitis: Regulation of the cholangiocyte secretome and downstream T cell differentiation
Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease. Approximately 30% of patients do not respond to therapy with ursodeoxycholic acid (UDCA). Previous studies have implicated increased senescence of cholangiocytes in patients who do not respond to UDCA. This may increase the rel...
Autores principales: | Etherington, Rachel E., Millar, Benjamin J. M., Innes, Barbara A., Jones, David E. J., Kirby, John A., Brain, John G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996327/ https://www.ncbi.nlm.nih.gov/pubmed/32123836 http://dx.doi.org/10.1096/fba.2018-00046 |
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