Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice

Icosabutate is a structurally engineered eicosapentaenoic acid derivative under development for nonalcoholic steatohepatitis (NASH). In this study, we investigated the absorption and distribution properties of icosabutate in relation to liver targeting and used rodents to evaluate the effects of ico...

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Detalles Bibliográficos
Autores principales: van den Hoek, Anita M., Pieterman, Elsbet J., van der Hoorn, José W., Iruarrizaga‐Lejarreta, Marta, Alonso, Cristina, Verschuren, Lars, Skjæret, Tore, Princen, Hans M.G., Fraser, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996349/
https://www.ncbi.nlm.nih.gov/pubmed/32025605
http://dx.doi.org/10.1002/hep4.1453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996349/
https://www.ncbi.nlm.nih.gov/pubmed/32025605
http://dx.doi.org/10.1002/hep4.1453

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