The snoRNA target of t(4;14) in multiple myeloma regulates ribosome biogenesis

The orphan small nucleolar RNA (snoRNA) ACA11 is overexpressed as a result of the t(4;14) chromosomal translocation in multiple myeloma (MM), increases reactive oxygen species, and drives cell proliferation. Like other snoRNAs, ACA11 is predominantly localized to a sub‐nuclear organelle, the nucleol...

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Detalles Bibliográficos
Autores principales: Oliveira, Vanessa, Mahajan, Nitin, Bates, Melissa L., Tripathi, Chakrapani, Kim, Kyusik Q., Zaher, Hani S., Maggi Jr, Leonard B., Tomasson, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996358/
https://www.ncbi.nlm.nih.gov/pubmed/32095781
http://dx.doi.org/10.1096/fba.2018-00075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996358/
https://www.ncbi.nlm.nih.gov/pubmed/32095781
http://dx.doi.org/10.1096/fba.2018-00075

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