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Histone chaperone HIRA dictate proliferation vs differentiation of chronic myeloid leukemia cells

Abnormal proliferation and disrupted differentiation of hematopoietic progenitors mark leukemia. Histone cell cycle regulator A (HIRA), a histone chaperone, regulates hemogenic to hematopoietic transition involved in normal hematopoiesis. But, its role remains unexplored in leukemia, a case of dysre...

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Detalles Bibliográficos
Autores principales: Majumder, Aditi, Dharan, Arya T., Baral, Ishita, Varghese, Pallavi Chinnu, Mukherjee, Ananda, Subhadradevi, Lakshmi, Narayanan, Geetha, Dutta, Debasree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996362/
https://www.ncbi.nlm.nih.gov/pubmed/32123848
http://dx.doi.org/10.1096/fba.2019-00014