AJP001, a novel helper T‐cell epitope, induces a humoral immune response with activation of innate immunity when included in a peptide vaccine

Vaccine design requires well‐tailored formulations including a T‐cell epitope and adjuvants. We identified a novel cationic peptide, AJP001, which possesses a strong affinity for murine MHC class II alleles (H2‐IE(d) and H2‐IA(d)) and low affinity for H2‐IA(b). We designed an AJP001 and epitope pept...

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Detalles Bibliográficos
Autores principales: Tenma, Akiko, Nakagami, Hironori, Tomioka, Hideki, Sakaguchi, Makoto, Ide, Ryoko, Koriyama, Hiroshi, Hayashi, Hiroki, Shimamura, Munehisa, Rakugi, Hiromi, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996369/
https://www.ncbi.nlm.nih.gov/pubmed/32123820
http://dx.doi.org/10.1096/fba.2019-00056

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