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Alpha‐Klotho, a critical protein for lung health, is not expressed in normal lung

Alpha‐Klotho (αKlotho), produced by the kidney and selected organs, is essential for tissue maintenance and protection. Homozygous αKlotho‐deficiency leads to premature multi‐organ degeneration and death; heterozygous insufficiency leads to apoptosis, oxidative stress, and increased injury susceptib...

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Detalles Bibliográficos
Autores principales: Zhang, Jianning, Cao, Khoa, Pastor, Johanne V., Li, Liping, Moe, Orson W., Hsia, Connie C. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996373/
https://www.ncbi.nlm.nih.gov/pubmed/32123814
http://dx.doi.org/10.1096/fba.2019-00016