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Glutathione increase by the n‐butanoyl glutathione derivative (GSH‐C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus

During aging, glutathione (GSH) content declines and the immune system undergoes a deficiency in the induction of Th1 response. Reduced secretion of Th1 cytokines, which is associated with GSH depletion, could weaken the host defenses against viral infections. We first evaluated the concentration of...

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Detalles Bibliográficos
Autores principales:	Amatore, Donatella, Celestino, Ignacio, Brundu, Serena, Galluzzi, Luca, Coluccio, Paolo, Checconi, Paola, Magnani, Mauro, Palamara, Anna Teresa, Fraternale, Alessandra, Nencioni, Lucia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996388/ https://www.ncbi.nlm.nih.gov/pubmed/32123833 http://dx.doi.org/10.1096/fba.2018-00066

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