Focal Adhesion Kinase Promotes Hepatic Stellate Cell Activation by Regulating Plasma Membrane Localization of TGFβ Receptor 2

Transforming growth factor β (TGFβ) induces hepatic stellate cell (HSC) differentiation into tumor‐promoting myofibroblast, although underlying mechanism remains incompletely understood. Focal adhesion kinase (FAK) is activated in response to TGFβ stimulation, so it transmits TGFβ stimulus to extrac...

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Detalles Bibliográficos
Autores principales: Chen, Yunru, Li, Qing, Tu, Kangsheng, Wang, Yuanguo, Wang, Xianghu, Liu, Dandan, Chen, Chen, Liu, Donglian, Yang, Rendong, Qiu, Wei, Kang, Ningling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996408/
https://www.ncbi.nlm.nih.gov/pubmed/32025610
http://dx.doi.org/10.1002/hep4.1452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996408/
https://www.ncbi.nlm.nih.gov/pubmed/32025610
http://dx.doi.org/10.1002/hep4.1452

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