miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation

Objectives: Macrophages are conventionally classified as pro-inflammatory (M1) and anti-inflammatory (M2) functional types. There is evidence for a predominance of macrophages with an inflammatory phenotype (M1) in the rheumatoid arthritis (RA) synovium. MicroRNAs (miRs) play a pivotal role in regul...

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Detalles Bibliográficos
Autores principales: Quero, Lilian, Tiaden, André N., Hanser, Edveena, Roux, Julien, Laski, Artur, Hall, Jonathan, Kyburz, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996464/
https://www.ncbi.nlm.nih.gov/pubmed/32047494
http://dx.doi.org/10.3389/fimmu.2019.03087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996464/
https://www.ncbi.nlm.nih.gov/pubmed/32047494
http://dx.doi.org/10.3389/fimmu.2019.03087

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