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miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation

Objectives: Macrophages are conventionally classified as pro-inflammatory (M1) and anti-inflammatory (M2) functional types. There is evidence for a predominance of macrophages with an inflammatory phenotype (M1) in the rheumatoid arthritis (RA) synovium. MicroRNAs (miRs) play a pivotal role in regul...

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Detalles Bibliográficos
Autores principales:	Quero, Lilian, Tiaden, André N., Hanser, Edveena, Roux, Julien, Laski, Artur, Hall, Jonathan, Kyburz, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996464/ https://www.ncbi.nlm.nih.gov/pubmed/32047494 http://dx.doi.org/10.3389/fimmu.2019.03087

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