Cargando…

Comparative Pharmacokinetics, Bioequivalence and Safety Study of Two Recombinant Human Chorionic Gonadotropin Injections in Healthy Chinese Subjects

OBJECTIVE: To evaluate the pharmacokinetics (PK), bioequivalence and safety profile of the recombinant human chorionic gonadotropin (r-hCG) injection formulation LZM003 (test drug) comparing with that of Ovidrel(®) (reference drug) in healthy Chinese subjects. METHODS: This is a randomized, single-b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jin, Yang, Tianli, Mei, Hekun, Yu, Xueming, Peng, Hongmei, Wang, Rui, Cai, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996485/ https://www.ncbi.nlm.nih.gov/pubmed/32099328 http://dx.doi.org/10.2147/DDDT.S235064

Ejemplares similares

Single‐dose pharmacokinetic study comparing the pharmacokinetics of recombinant human chorionic gonadotropin in healthy Japanese and Caucasian women and recombinant human chorionic gonadotropin and urinary human chorionic gonadotropin in healthy Japanese women
por: Bagchus, Wilhelmina, et al.
Publicado: (2017)

Randomized Pharmacokinetic Study of a Highly Purified Human Chorionic Gonadotropin and of a Recombinant Human Chorionic Gonadotropin Following Single Subcutaneous Administration in Healthy Women
por: Radicioni, Milko, et al.
Publicado: (2022)

Pharmacokinetic and Bioequivalence Study of Eldecalcitol Soft Capsules in Healthy Chinese Subjects
por: Li, Ting, et al.
Publicado: (2022)

Evaluation of pharmacokinetics and safety with bioequivalence of Amlodipine in healthy Chinese volunteers: Bioequivalence Study Findings
por: Wang, Tongtong, et al.
Publicado: (2020)

Pharmacokinetics, Bioequivalence and Safety of Cloperastine in Chinese Healthy Subjects Under Fasting and Postprandial Conditions
por: Luo, Hong-Yu, et al.
Publicado: (2022)

Evaluation of the Highly Variable Agomelatine Pharmacokinetics in Chinese Healthy Subjects to Support Bioequivalence Study
por: Pei, Qi, et al.
Publicado: (2014)

Pharmacokinetics, Bioequivalence and Safety Evaluation of Two Ticagrelor Tablets Under Fasting and Fed Conditions in Healthy Chinese Subjects
por: Wang, Jin, et al.
Publicado: (2021)

Pharmacokinetics and bioequivalence of sunitinib and Sutent(®) in Chinese healthy subjects: an open-label, randomized, crossover study
por: Wang, Yanli, et al.
Publicado: (2023)

Evaluation of Pharmacokinetics and Safety with Bioequivalence of Ibuprofen Sustained-Release Capsules of Two Formulations, in Chinese Healthy Volunteers: Bioequivalence Study
por: Huang, Chunqi, et al.
Publicado: (2023)

Fertility Rates of Ewes Treated with Medroxyprogesterone and Injected with Equine Chorionic Gonadotropin plus Human Chorionic Gonadotropin in Anoestrous Season
por: Santos, I. W., et al.
Publicado: (2010)

Bioequivalence of the pharmacokinetics between tofacitinib aspartate and tofacitinib citrate in healthy subjects
por: Shin, Wonsuk, et al.
Publicado: (2020)

Bioequivalence and Pharmacokinetic Profiles of Generic and Branded Obeticholic Acid in Healthy Chinese Subjects Under Fasting and Fed Conditions
por: Wang, Meng-Na, et al.
Publicado: (2021)

First‐in‐human trial assessing the pharmacokinetic‐pharmacodynamic profile of a novel recombinant human chorionic gonadotropin in healthy women and men of reproductive age
por: Broksø Kyhl, Lars‐Erik, et al.
Publicado: (2021)

Pharmacokinetic properties and bioequivalence of gefitinib 250 mg in healthy Korean male subjects
por: Moon, Seol Ju, et al.
Publicado: (2021)

Safety, Tolerability, and Pharmacokinetics of Recombinant Human Neuregulin-1 in Healthy Chinese Subjects
por: Xu, Junyu, et al.
Publicado: (2023)

Dual trigger with gonadotropin-releasing hormone agonist and recombinant human chorionic gonadotropin improves the outcome of intrauterine insemination
por: Halim, Binarwan, et al.
Publicado: (2022)

Pharmacokinetics of oral pridinol: Results of a randomized, crossover bioequivalence trial in healthy subjects
por: Richter, Maren, et al.
Publicado: (2021)

Pharmacogenetic Variants Associated with Fluoxetine Pharmacokinetics from a Bioequivalence Study in Healthy Subjects
por: Díaz-Tufinio, Carlos Alejandro, et al.
Publicado: (2023)

Satisfaction and usability of the recombinant chorionic gonadotropin prefilled pen: a survey in Italy
por: Dallagiovanna, Chiara, et al.
Publicado: (2022)

Pharmacokinetics and bioequivalence of Ezetimibe tablet versus Ezetrol®:an open-label, randomized, two-sequence crossover study in healthy Chinese subjects
por: Sun, Feifei, et al.
Publicado: (2023)

Evaluation of Bioequivalency and Pharmacokinetic Parameters for Two Formulations of Glimepiride 1-mg in Chinese Subjects
por: Ju, Gehang, et al.
Publicado: (2020)

Experimental Production of Gynecomastia with Chorionic Gonadotropin
por: Klatskin, Gerald, et al.
Publicado: (1952)

Chorionic gonadotropin and uterine dialogue in the primate
por: Cameo, Paula, et al.
Publicado: (2004)

IMMUNOHISTOCHEMICAL LOCALIZATION OF HUMAN CHORIONIC GONADOTROPIN
por: Midgley, A. R., et al.
Publicado: (1962)

Human Chorionic Gonadotropin and Breast Cancer
por: Schüler-Toprak, Susanne, et al.
Publicado: (2017)

Production of Mare Chorionic Girdle Organoids That Secrete Equine Chorionic Gonadotropin
por: Thompson, Riley E., et al.
Publicado: (2023)

Pharmacokinetics and Safety of Follitropin Delta in Gonadotropin Down-Regulated Healthy Chinese Women
por: Shao, Feng, et al.
Publicado: (2022)

Pharmacokinetics and bioequivalence evaluation of omeprazole and sodium bicarbonate dry suspensions in healthy Chinese volunteers
por: Zhang, Rui, et al.
Publicado: (2023)

Pharmacokinetics and Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Crossover Study
por: Shi, Ping, et al.
Publicado: (2021)

Pharmacokinetics and Bioequivalence of Two Empagliflozin, with Evaluation in Healthy Jordanian Subjects under Fasting and Fed Conditions
por: Hailat, Mohammad, et al.
Publicado: (2022)

Bioequivalence and Bioavailability of an Orodispersible Tablet of Sildenafil Citrate in Healthy Chinese Male Subjects
por: Lv, Yuan, et al.
Publicado: (2020)

Bioequivalence of two esomeprazole magnesium enteric-coated formulations in healthy Chinese subjects
por: Liu, Zheng-Zhi, et al.
Publicado: (2020)

The relationship between the variants in the 5′-untranslated regions of equine chorionic gonadotropin genes and serum equine chorionic gonadotropin levels
por: Liu, ShuQin, et al.
Publicado: (2017)

Evaluation of the Bioequivalence of Acarbose in Healthy Chinese People
por: Chen, Yan, et al.
Publicado: (2021)

Pharmacokinetics and bioequivalence of two imidocarb formulations in cattle after subcutaneous injection
por: Wang, Honglei, et al.
Publicado: (2022)

Therapeutic Drug Monitoring of Tigecycline in 67 Infected Patients and a Population Pharmacokinetics/Microbiological Evaluation of A. baumannii Study
por: Yang, Tianli, et al.
Publicado: (2021)

Human Chorionic Gonadotropin: The Pregnancy Hormone and More
por: Theofanakis, Charalampos, et al.
Publicado: (2017)

Human Chorionic Gonadotropin and Early Embryogenesis: Review
por: d’Hauterive, Sophie Perrier, et al.
Publicado: (2022)

INTRAUTERINE INJECTION OF HUMAN CHORIONIC GONADOTROPIN BEFORE EMBRYO TRANSFER: A RANDOMIZED CONTROLLED TRIAL
por: Abdallah, Karim S., et al.
Publicado: (2020)

Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions
por: Ding, Ying, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_d4ihg9vb3g1kdgr1i4g0pcreqb