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Dramatic increase in gene mutational burden after transformation of follicular lymphoma into TdT(+) B-lymphoblastic leukemia/lymphoma

Transformation of follicular lymphoma (FL) into B-lymphoblastic leukemia/lymphoma (B-ALL/LBL) is rare and results in greatly increased aggressiveness of clinical course. Here we present extensive molecular analysis of this unusual transformation, including immunoglobulin (Ig) gene rearrangement stud...

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Detalles Bibliográficos
Autores principales: Belman, Jonathan P., Meng, Wenzhao, Wang, Hong Yi, Li, Jie, Strauser, Honore T., Rosenfeld, Aaron M., Zhang, Qian, Prak, Eline T. Luning, Wasik, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996523/
https://www.ncbi.nlm.nih.gov/pubmed/31776129
http://dx.doi.org/10.1101/mcs.a004614