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Dramatic increase in gene mutational burden after transformation of follicular lymphoma into TdT(+) B-lymphoblastic leukemia/lymphoma
Transformation of follicular lymphoma (FL) into B-lymphoblastic leukemia/lymphoma (B-ALL/LBL) is rare and results in greatly increased aggressiveness of clinical course. Here we present extensive molecular analysis of this unusual transformation, including immunoglobulin (Ig) gene rearrangement stud...
Autores principales: | Belman, Jonathan P., Meng, Wenzhao, Wang, Hong Yi, Li, Jie, Strauser, Honore T., Rosenfeld, Aaron M., Zhang, Qian, Prak, Eline T. Luning, Wasik, Mariusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996523/ https://www.ncbi.nlm.nih.gov/pubmed/31776129 http://dx.doi.org/10.1101/mcs.a004614 |
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