New insights into the pathogenesis of leprosy: contribution of subversion of host cell metabolism to bacterial persistence, disease progression, and transmission

Chronic infection by the obligate intracellular pathogen Mycobacterium leprae may lead to the development of leprosy. Of note, in the lepromatous clinical form of the disease, failure of the immune system to constrain infection allows the pathogen to reproduce to very high numbers with minimal clini...

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Detalles Bibliográficos
Autores principales: de Macedo, Cristiana Santos, Lara, Flavio Alves, Pinheiro, Roberta Olmo, Schmitz, Veronica, de Berrêdo-Pinho, Marcia, Pereira, Geraldo Moura, Pessolani, Maria Cristina Vidal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996526/
https://www.ncbi.nlm.nih.gov/pubmed/32051758
http://dx.doi.org/10.12688/f1000research.21383.1

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