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Inhibition of fibroblast secreted QSOX1 perturbs extracellular matrix in the tumor microenvironment and decreases tumor growth and metastasis in murine cancer models
Extracellular matrix (ECM) plays an important role in tumor development and dissemination, but few points of therapeutic intervention targeting ECM of the tumor microenvironment have been exploited to date. Recent observations suggest that the enzymatic introduction of disulfide bond cross-links int...
Autores principales: | Feldman, Tal, Grossman-Haham, Iris, Elkis, Yoav, Vilela, Patrick, Moskovits, Neta, Barshack, Iris, Salame, Tomer M., Fass, Deborah, Ilani, Tal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996906/ https://www.ncbi.nlm.nih.gov/pubmed/32064042 http://dx.doi.org/10.18632/oncotarget.27438 |
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