Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery

There is a compelling need for new therapeutic strategies for glioblastoma multiforme (GBM). Preclinical target and therapeutic discovery for GBMs is primarily conducted using cell lines grown in serum-containing media, such as U-87 MG, which do not reflect the gene expression profiles of tumors fou...

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Detalles Bibliográficos
Autores principales: Ye, Ling F., Reznik, Eduard, Korn, Joshua M., Lin, Fallon, Yang, Guizhi, Malesky, Kimberly, Gao, Hui, Loo, Alice, Pagliarini, Raymond, Mikkelsen, Tom, Lo, Donald C., deCarvalho, Ana C., Stockwell, Brent R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996910/
https://www.ncbi.nlm.nih.gov/pubmed/32064048
http://dx.doi.org/10.18632/oncotarget.27457

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