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FOXL2 homozygous genotype and chromosome instability are associated with recurrence in adult granulosa cell tumors of the ovary
Introduction: Adult granulosa cell tumors (aGCTs) are extremely rare tumors characterized by the presence of the single missense mutation (c.402 C>G, p. C134W) in the FOXL2 gene. These tumors are frequently associated with a slow, indolent disease progression and a high probability of aggressive...
Autores principales: | Kraus, Francois, Dremaux, Julie, Altakfi, Wajd, Goux, Magalie, Pontois, Léa, Sevestre, Henri, Trudel, Stéphanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996913/ https://www.ncbi.nlm.nih.gov/pubmed/32064045 http://dx.doi.org/10.18632/oncotarget.27447 |
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