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FOXL2 homozygous genotype and chromosome instability are associated with recurrence in adult granulosa cell tumors of the ovary

Introduction: Adult granulosa cell tumors (aGCTs) are extremely rare tumors characterized by the presence of the single missense mutation (c.402 C>G, p. C134W) in the FOXL2 gene. These tumors are frequently associated with a slow, indolent disease progression and a high probability of aggressive...

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Detalles Bibliográficos
Autores principales: Kraus, Francois, Dremaux, Julie, Altakfi, Wajd, Goux, Magalie, Pontois, Léa, Sevestre, Henri, Trudel, Stéphanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996913/
https://www.ncbi.nlm.nih.gov/pubmed/32064045
http://dx.doi.org/10.18632/oncotarget.27447

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