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Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models

Background: Monoclonal antibody (mAb) 6G5j is a novel anti-CEACAM monoclonal antibody. Our aim was to investigate mAb 6G5j binding characteristics and to validate fluorescence targeting of colorectal tumors and metastases in patient derived orthotopic xenograft (PDOX) models with fluorescently label...

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Detalles Bibliográficos
Autores principales:	Hollandsworth, Hannah M., Amirfakhri, Siamak, Filemoni, Filemoni, Schmitt, Verena, Wennemuth, Gunther, Schmidt, Alexej, Hoffman, Robert M., Singer, Bernhard B., Bouvet, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996915/ https://www.ncbi.nlm.nih.gov/pubmed/32064046 http://dx.doi.org/10.18632/oncotarget.27446

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