Cargando…

Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models

Background: Monoclonal antibody (mAb) 6G5j is a novel anti-CEACAM monoclonal antibody. Our aim was to investigate mAb 6G5j binding characteristics and to validate fluorescence targeting of colorectal tumors and metastases in patient derived orthotopic xenograft (PDOX) models with fluorescently label...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hollandsworth, Hannah M., Amirfakhri, Siamak, Filemoni, Filemoni, Schmitt, Verena, Wennemuth, Gunther, Schmidt, Alexej, Hoffman, Robert M., Singer, Bernhard B., Bouvet, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996915/ https://www.ncbi.nlm.nih.gov/pubmed/32064046 http://dx.doi.org/10.18632/oncotarget.27446

Ejemplares similares

Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adhesion molecules
por: Hollandsworth, Hannah M., et al.
Publicado: (2020)

Near-infrared photoimmunotherapy is effective treatment for colorectal cancer in orthotopic nude-mouse models
por: Hollandsworth, Hannah M., et al.
Publicado: (2020)

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model
por: Lwin, Thinzar M., et al.
Publicado: (2018)

Monocytes engineered with iSNAP inhibit human B‐lymphoma progression
por: Wu, Haohsiang, et al.
Publicado: (2022)

Proof of Principle of Combining Fluorescence-Guided Surgery with Photoimmunotherapy to Improve the Outcome of Pancreatic Cancer Therapy in an Orthotopic Mouse Model
por: Nishino, Hiroto, et al.
Publicado: (2022)

Fluorescence Molecular Targeting of Colon Cancer to Visualize the Invisible
por: Lwin, Thinzar M., et al.
Publicado: (2022)

Fluorescent Anti-CEA Nanobody for Rapid Tumor-Targeting and Imaging in Mouse Models of Pancreatic Cancer
por: Lwin, Thinzar M., et al.
Publicado: (2022)

The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review
por: Turner, Michael A., et al.
Publicado: (2021)

Complementarity of ultrasound and fluorescence imaging in an orthotopic mouse model of pancreatic cancer
por: Snyder, Cynthia S, et al.
Publicado: (2009)

Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma †
por: Hoffman, Robert M.
Publicado: (2017)

Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models
por: Murakami, Takashi, et al.
Publicado: (2015)

Fluorescence laparoscopy imaging of pancreatic tumor progression in an orthotopic mouse model
por: Tran Cao, Hop S., et al.
Publicado: (2010)

46. PAN-CANCER ANALYSIS OF ORTHOTOPIC PATIENT DERIVED XENOGRAFTS FROM BRAIN METASTASES
por: Zeng, Yu, et al.
Publicado: (2020)

Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery
por: Yano, Shuya, et al.
Publicado: (2015)

Temozolomide and Pazopanib Combined with FOLFOX Regressed a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model
por: Zhu, Guangwei, et al.
Publicado: (2020)

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models
por: Yano, Shuya, et al.
Publicado: (2015)

Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model
por: Yamamoto, Mako, et al.
Publicado: (2016)

MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX)
por: Kawaguchi, Kei, et al.
Publicado: (2017)

Acinetobacter baumannii Targets Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules (CEACAMs) for Invasion of Pneumocytes
por: Ambrosi, Cecilia, et al.
Publicado: (2020)

The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model
por: Higuchi, Takashi, et al.
Publicado: (2019)

Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen.
por: Moshakis, V., et al.
Publicado: (1981)

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models
por: Park, Jeong Youp, et al.
Publicado: (2016)

Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models
por: Park, Jeong Youp, et al.
Publicado: (2016)

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts
por: Jäger, Wolfgang, et al.
Publicado: (2014)

Development and characterization of a human orthotopic neuroblastoma xenograft
por: Stewart, Elizabeth, et al.
Publicado: (2015)

Orthotopic Patient-Derived Xenografts of Pediatric Solid Tumors
por: Stewart, Elizabeth, et al.
Publicado: (2017)

Orthotopic tumours, a hot topic for xenograft models?
por: Zheng, Dali
Publicado: (2019)

Insecticide use pattern and phenotypic susceptibility of Anopheles gambiae sensu lato to commonly used insecticides in Lower Moshi, northern Tanzania
por: Nnko, Elinas J., et al.
Publicado: (2017)

Investigating circulating tumor cells and distant metastases in patient-derived orthotopic xenograft models of triple-negative breast cancer
por: Ramani, Vishnu C., et al.
Publicado: (2019)

Polyethylene Glycol (PEG) Linked to Near Infrared (NIR) Dyes Conjugated to Chimeric Anti-Carcinoembryonic Antigen (CEA) Antibody Enhances Imaging of Liver Metastases in a Nude-Mouse Model of Human Colon Cancer
por: Maawy, Ali A., et al.
Publicado: (2014)

Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application
por: Higuchi, Takashi, et al.
Publicado: (2022)

An orthotopic xenograft model of human nonseminomatous germ cell tumour
por: Douglas, M L, et al.
Publicado: (2001)

Dynamic Quantitative T1 Mapping in Orthotopic Brain Tumor Xenografts()
por: Herrmann, Kelsey, et al.
Publicado: (2016)

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Murakami, Takashi, et al.
Publicado: (2017)

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts
por: Hoover, Malachia, et al.
Publicado: (2016)

Effect of Different Hosts on Feeding Patterns and Mortality of Mosquitoes (Diptera: Culicidae) and their Implications on Parasite Transmission
por: Kweka, Eliningaya J, et al.
Publicado: (2010)

IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts
por: Kurbegovic, Sorel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cbi6nq2abcj53i6vsneu713baq