Tumor suppressor genes and allele-specific expression: mechanisms and significance

Recent findings indicate that allele-specific expression (ASE) at specific cancer driver gene loci may be of importance in onset/progression of the disease. Of particular interest are loss-of-function (LOF) of tumor suppressor gene (TSGs) alleles. While LOF tumor suppressor mutations are typically c...

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Detalles Bibliográficos
Autores principales: Clayton, Evan A., Khalid, Shareef, Ban, Dongjo, Wang, Lu, Jordan, I. King, McDonald, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996918/
https://www.ncbi.nlm.nih.gov/pubmed/32064050
http://dx.doi.org/10.18632/oncotarget.27468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996918/
https://www.ncbi.nlm.nih.gov/pubmed/32064050
http://dx.doi.org/10.18632/oncotarget.27468

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