1,25‐Dihydroxyvitamin D protects against age‐related osteoporosis by a novel VDR‐Ezh2‐p16 signal axis

To determine whether 1,25‐dihydroxyvitamin D (1,25(OH)(2)D) can exert an anti‐osteoporosis role through anti‐aging mechanisms, we analyzed the bone phenotype of mice with 1,25(OH)(2)D deficiency due to deletion of the enzyme, 25‐hydroxyvitamin D 1α‐hydroxylase, while on a rescue diet. 1,25(OH)(2)D d...

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Detalles Bibliográficos
Autores principales: Yang, Renlei, Chen, Jie, Zhang, Jiao, Qin, Ran, Wang, Rong, Qiu, Yue, Mao, Zhiyuan, Goltzman, David, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996957/
https://www.ncbi.nlm.nih.gov/pubmed/31880094
http://dx.doi.org/10.1111/acel.13095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996957/
https://www.ncbi.nlm.nih.gov/pubmed/31880094
http://dx.doi.org/10.1111/acel.13095

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