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Metformin mediates cardioprotection against aging‐induced ischemic necroptosis

Necroptosis is crucially involved in severe cardiac pathological conditions. However, whether necroptosis contributes to age‐related intolerance to ischemia/reperfusion (I/R) injury remains elusive. In addition, metformin as a potential anti‐aging related injury drug, how it interacts with myocardia...

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Detalles Bibliográficos
Autores principales: Li, Chen, Mu, Nan, Gu, Chunhu, Liu, Manling, Yang, Zheng, Yin, Yue, Chen, Mai, Wang, Yishi, Han, Yuehu, Yu, Lu, Ma, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996959/
https://www.ncbi.nlm.nih.gov/pubmed/31944526
http://dx.doi.org/10.1111/acel.13096