Cargando…

Downregulation of Rab17 promotes cell proliferation and invasion in non‐small cell lung cancer through STAT3/HIF‐1α/VEGF signaling

BACKGROUND: Rab GTPases play a key role in regulating intercellular vesicle trafficking in both exo‐ and endocytic pathways. Recent studies have reported that Rab small GTPases and the associated regulatory proteins and effectors are involved in many cancers. The purpose of this study was to investi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Mingliang, Wang, Wendong, Ding, Jingmin, Wang, Jiashun, Zhang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997001/ https://www.ncbi.nlm.nih.gov/pubmed/31841274 http://dx.doi.org/10.1111/1759-7714.13278

Ejemplares similares

MicroRNA-20b Downregulates HIF-1α and Inhibits the Proliferation and Invasion of Osteosarcoma Cells
por: Liu, Ming, et al.
Publicado: (2016)

Hyperoxia sensitizes hypoxic HeLa cells to ionizing radiation by downregulating HIF-1α and VEGF expression
por: Dong, Dan, et al.
Publicado: (2021)

Curcumin induces apoptosis in human hepatocellular carcinoma cells by decreasing the expression of STAT3/VEGF/HIF-1α signaling
por: Wang, Xiaoping, et al.
Publicado: (2023)

Downregulation of HIF-1α inhibits the proliferation and invasion of non-small cell lung cancer NCI-H157 cells
por: QIAN, JIALIN, et al.
Publicado: (2016)

Everolimus downregulates STAT3/HIF-1α/VEGF pathway to inhibit angiogenesis and lymphangiogenesis in TP53 mutant head and neck squamous cell carcinoma (HNSCC)
por: Alam, Md Maksudul, et al.
Publicado: (2023)

SHMT2 Promotes Gastric Cancer Development through Regulation of HIF1α/VEGF/STAT3 Signaling
por: Wang, Weida, et al.
Publicado: (2023)

HIF-1α Contributes to Proliferation and Invasiveness of Neuroblastoma Cells via SHH Signaling
por: Chen, Sheng, et al.
Publicado: (2015)

Benzyl Isothiocyanate Suppresses Pancreatic Tumor Angiogenesis and Invasion by Inhibiting HIF-α/VEGF/Rho-GTPases: Pivotal Role of STAT-3
por: Boreddy, Srinivas Reddy, et al.
Publicado: (2011)

JMJD2C-mediated long non-coding RNA MALAT1/microRNA-503-5p/SEPT2 axis worsens non-small cell lung cancer
por: Zhang, Jun, et al.
Publicado: (2022)

Relationship between the expression of CD133, HIF-1α, VEGF and the proliferation and apoptosis in hypoxic human prostate cancer cells
por: Liu, Lingyun, et al.
Publicado: (2017)

ELTD1 facilitates glioma proliferation, migration and invasion by activating JAK/STAT3/HIF-1α signaling axis
por: Li, Junjun, et al.
Publicado: (2019)

A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells
por: Rathinavelu, Appu, et al.
Publicado: (2012)

Rab18 Regulates Proliferation, Invasion and Cisplatin Sensitivity Through STAT3 Signaling in Head and Neck Squamous Cell Carcinoma
por: Ji, Xu, et al.
Publicado: (2020)

SOCS3 blocks HIF-1α expression to inhibit proliferation and angiogenesis of human small cell lung cancer by downregulating activation of Akt, but not STAT3
por: WAN, JUN, et al.
Publicado: (2015)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

Nicotine Promotes Proliferation of Human Nasopharyngeal Carcinoma Cells by Regulating α7AChR, ERK, HIF-1α and VEGF/PEDF Signaling
por: Shi, Dingbo, et al.
Publicado: (2012)

Curcumin induces apoptosis and inhibits proliferation in infantile hemangioma endothelial cells via downregulation of MCL-1 and HIF-1α
por: Lou, Suhui, et al.
Publicado: (2018)

Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells
por: Fuady, Jerry H., et al.
Publicado: (2016)

Copper activates HIF-1α/GPER/VEGF signalling in cancer cells
por: Rigiracciolo, Damiano Cosimo, et al.
Publicado: (2015)

Novel Nargenicin A1 Analog Inhibits Angiogenesis by Downregulating the Endothelial VEGF/VEGFR2 Signaling and Tumoral HIF-1α/VEGF Pathway
por: Han, Jang Mi, et al.
Publicado: (2020)

HIF-2α regulates proliferation, invasion, and metastasis of hepatocellular carcinoma cells via VEGF/Notch1 signaling axis after insufficient radiofrequency ablation
por: Yang, Yongguang, et al.
Publicado: (2022)

Effects of testosterone on the expression levels of AMH, VEGF and HIF-1α in mouse granulosa cells
por: Zhang, Ying, et al.
Publicado: (2016)

(Immunohistochemical study of STAT3, HIF-1α and VEGF in pterygium and normal conjunctiva: Experimental research and literature review)
por: Dong, Shiqi, et al.
Publicado: (2020)

Resveratrol Suppresses Tumor Progression via Inhibiting STAT3/HIF-1α/VEGF Pathway in an Orthotopic Rat Model of Non-Small-Cell Lung Cancer (NSCLC)
por: Wang, Huixia, et al.
Publicado: (2020)

Correction: Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2α in invasive breast cancer cells
por: Fuady, Jerry H., et al.
Publicado: (2017)

Hypoxia preconditioning protection of corneal stromal cells requires HIF1α but not VEGF
por: Xing, Dongmei, et al.
Publicado: (2009)

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression
por: Palazon, Asis, et al.
Publicado: (2017)

Digoxin Downregulates NDRG1 and VEGF through the Inhibition of HIF-1α under Hypoxic Conditions in Human Lung Adenocarcinoma A549 Cells
por: Wei, Dong, et al.
Publicado: (2013)

Quercetin Downregulates Cyclooxygenase-2 Expression and HIF-1α/VEGF Signaling-Related Angiogenesis in a Mouse Model of Abdominal Aortic Aneurysm
por: Wang, Lian, et al.
Publicado: (2020)

HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance
por: Shi, Bin, et al.
Publicado: (2022)

RAB27A promotes the proliferation and invasion of colorectal cancer cells
por: Li, Qingyan, et al.
Publicado: (2022)

Effect of Moxibustion on HIF-1α and VEGF Levels in Patients with Rheumatoid Arthritis
por: Gong, Yuanyuan, et al.
Publicado: (2019)

Down-regulation of HIF-1α inhibits the proliferation, migration, and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression
por: Zhang, Jingjing, et al.
Publicado: (2018)

MicroRNA-206 attenuates the growth and angiogenesis in non-small cell lung cancer cells by blocking the 14-3-3ζ/STAT3/HIF-1α/VEGF signaling
por: Xue, Dong, et al.
Publicado: (2016)

Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway
por: Yan, Xianke, et al.
Publicado: (2020)

Expression of HIF-2α and VEGF in Cervical Squamous Cell Carcinoma and Its Clinical Significance
por: Zhang, Lixia, et al.
Publicado: (2016)

EGCG Attenuates Autoimmune Arthritis by Inhibition of STAT3 and HIF-1α with Th17/Treg Control
por: Yang, Eun-Ji, et al.
Publicado: (2014)

Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling
por: Liu, Peng, et al.
Publicado: (2017)

Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways
por: Wang, Ran-Ran, et al.
Publicado: (2022)

Clinicopathologic Significance of HIF-1α, CXCR4, and VEGF Expression in Colon Cancer
por: Wu, Yugang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_er4tsg45ks7kh438lbpqap4io6