Jupiter microtubule‐associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers

Preoperative use of metformin in obese women with endometrioid endometrial cancer (EEC) reduces tumor proliferation and inhibits the mammalian target of rapamycin pathway, though is only effective in select cases. This study sought to identify a predictive and/or pharmacodynamic proteomic signature...

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Detalles Bibliográficos
Autores principales: Bateman, Nicholas W., Teng, Pang‐Ning, Hope, Erica, Hood, Brian L., Oliver, Julie, Ao, Wei, Zhou, Ming, Wang, Guisong, Tommarello, Domenic, Wilson, Katlin, Litzy, Tracy, Conrads, Kelly A., Hamilton, Chad A., Darcy, Kathleen M., Casablanca, Yovanni, Maxwell, George Larry, Bae‐Jump, Victoria, Conrads, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997075/
https://www.ncbi.nlm.nih.gov/pubmed/31808620
http://dx.doi.org/10.1002/cam4.2729

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