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98% IGHV gene identity is the optimal cutoff to dichotomize the prognosis of Chinese patients with chronic lymphocytic leukemia

Immunoglobulin heavy chain variable region (IGHV) mutational status has been an important prognostic factor for chronic lymphocytic leukemia (CLL) for decades. Patients with unmutated IGHV (≥98% identity to the germline sequence) have inferior prognosis and tend to carry unfavorable genetic markers...

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Detalles Bibliográficos
Autores principales:	Shi, Ke, Sun, Qian, Qiao, Chun, Zhu, Huayuan, Wang, Li, Wu, Jiazhu, Wang, Lili, Fu, Jianxin, Young, Ken H., Fan, Lei, Xia, Yi, Xu, Wei, Li, Jianyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997101/ https://www.ncbi.nlm.nih.gov/pubmed/31849198 http://dx.doi.org/10.1002/cam4.2788

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