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Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production
Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of polyketide production.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
KeAi Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997112/ https://www.ncbi.nlm.nih.gov/pubmed/32042931 http://dx.doi.org/10.1016/j.synbio.2020.01.002 |
| Sumario: | Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of polyketide production. |
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