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Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids
Nrf2 is a basic leucine zipper transcription factor that binds to the promoter region of the antioxidant response element (ARE), inducing the coordinated up-regulation of antioxidant and detoxification genes. We recently synthesized a set of new molecules by combining the functional moieties of curc...
Autores principales: | Serafini, Melania Maria, Catanzaro, Michele, Fagiani, Francesca, Simoni, Elena, Caporaso, Roberta, Dacrema, Marco, Romanoni, Irene, Govoni, Stefano, Racchi, Marco, Daglia, Maria, Rosini, Michela, Lanni, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997134/ https://www.ncbi.nlm.nih.gov/pubmed/32047434 http://dx.doi.org/10.3389/fphar.2019.01597 |
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