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Albumin Levels in Tear Film Modulate the Bioavailability of Medically-Relevant Topical Drugs

The breakdown of blood-tear barrier that occurs with ocular pathology allows for large amounts of albumin to leak into the tear fluid. This process likely represents an important restriction to drug absorption in ophthalmology, as only the unbound drug is transported across the ocular tissue barrier...

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Detalles Bibliográficos
Autores principales: Sebbag, Lionel, Moody, Leah M., Mochel, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997149/
https://www.ncbi.nlm.nih.gov/pubmed/32047429
http://dx.doi.org/10.3389/fphar.2019.01560