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Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Previously we demonstrated that the multiple sclerosis drug dimethyl fumarate (DMF) and its plasma breakdown product MMF could interact with chemotherapeutic agents to kill both GBM cells and activated microglia. The trial NCT02337426 demonstrated the safety of DMF in newly diagnosed GBM patients wh...

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Detalles Bibliográficos
Autores principales:	Dent, Paul, Booth, Laurence, Roberts, Jane L., Poklepovic, Andrew, Hancock, John F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997152/ https://www.ncbi.nlm.nih.gov/pubmed/32047722 http://dx.doi.org/10.3389/fonc.2020.00022

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