Phenprocoumon Dose Requirements, Dose Stability and Time in Therapeutic Range in Elderly Patients With CYP2C9 and VKORC1 Polymorphisms

BACKGROUND: Dose requirements of vitamin K antagonists are associated with CYP2C9 and VKORC1, but, compared to warfarin, less data is available about phenprocoumon. Furthermore, the effects on dose stability and anticoagulation quality are still unclear. METHODS: Aim was to scrutinize phenprocoumon...

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Detalles Bibliográficos
Autores principales: Schneider, Katharina Luise, Kunst, Melanie, Leuchs, Ann-Kristin, Böhme, Miriam, Weckbecker, Klaus, Kastenmüller, Kathrin, Bleckwenn, Markus, Holdenrieder, Stefan, Coch, Christoph, Hartmann, Gunther, Stingl, Julia Carolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997201/
https://www.ncbi.nlm.nih.gov/pubmed/32047440
http://dx.doi.org/10.3389/fphar.2019.01620

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