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Conversion of walnut tyrosinase into a catechol oxidase by site directed mutagenesis

Polyphenol oxidases (PPOs) comprise tyrosinases (TYRs) and catechol oxidases (COs), which catalyse the initial reactions in the biosynthesis of melanin. TYRs hydroxylate monophenolic (monophenolase activity) and oxidize diphenolic (diphenolase activity) substrates, whereas COs react only with diphen...

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Detalles Bibliográficos
Autores principales: Panis, Felix, Kampatsikas, Ioannis, Bijelic, Aleksandar, Rompel, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997208/
https://www.ncbi.nlm.nih.gov/pubmed/32015350
http://dx.doi.org/10.1038/s41598-020-57671-x

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