Dexmedetomidine Promotes Hippocampal Neurogenesis and Improves Spatial Learning and Memory in Neonatal Rats

BACKGROUND: Dexmedetomidine (Dex) is a highly selective α2-adrenoceptor agonist used as an off-label medication for pediatric sedation and analgesia. Recently, Dex was reported to exhibit neuroprotective efficacy in several brain injury models. Here we investigate whether neonatal Dex administration...

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Detalles Bibliográficos
Autores principales: Zhang, Yahan, Gao, Qiushi, Wu, Ziyi, Xue, Hang, Liu, Bo, Zhao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997224/
https://www.ncbi.nlm.nih.gov/pubmed/32099322
http://dx.doi.org/10.2147/DDDT.S228220

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