Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners

PURPOSE: Phosphoinositide 3-kinase (PI3K)-δ-dependent Akt activation is known to play critical roles in various immune responses of white blood cells in which PI3K-δ isoform is mostly expressed in contrast to the classes IA PI3Ks p110α and p110β. However, the immunological role of PI3K-δ isoform is...

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Detalles Bibliográficos
Autores principales: Kim, So Ri, Park, Hae Jin, Lee, Kyung Bae, Kim, Hee Jung, Jeong, Jae Seok, Cho, Seong Ho, Lee, Yong Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997282/
https://www.ncbi.nlm.nih.gov/pubmed/32009326
http://dx.doi.org/10.4168/aair.2020.12.2.338

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