Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is one of the most common monogenic disorders, characterized by the progressive formation of fluid-filled cysts. Tolvaptan is an approved drug for ADPKD patients, but is also associated with multiple side effects. The peroxisome proliferator-activ...

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Detalles Bibliográficos
Autores principales: Kanhai, Anish A., Bange, Hester, Verburg, Lotte, Dijkstra, Kyra L., Price, Leo S., Peters, Dorien J. M., Leonhard, Wouter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997373/
https://www.ncbi.nlm.nih.gov/pubmed/32015419
http://dx.doi.org/10.1038/s41598-020-58382-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997373/
https://www.ncbi.nlm.nih.gov/pubmed/32015419
http://dx.doi.org/10.1038/s41598-020-58382-z

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