Cargando…
The association between an increase in glucose levels and armed conflict-related stress: A population-based study
Studies have shown stress may lead to diabetes-related morbidities. In recent years during enhanced hostility periods, the population of Southern Israel experienced alert sirens and rocket fire on a daily basis. We investigated whether the exposure to these stressful circumstances, which peaked duri...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997375/ https://www.ncbi.nlm.nih.gov/pubmed/32015387 http://dx.doi.org/10.1038/s41598-020-58679-z |
_version_ | 1783493683227656192 |
---|---|
author | Yitshak-Sade, Maayan Mendelson, Nitsan Novack, Victor Codish, Shlomi Liberty, Idit F. |
author_facet | Yitshak-Sade, Maayan Mendelson, Nitsan Novack, Victor Codish, Shlomi Liberty, Idit F. |
author_sort | Yitshak-Sade, Maayan |
collection | PubMed |
description | Studies have shown stress may lead to diabetes-related morbidities. In recent years during enhanced hostility periods, the population of Southern Israel experienced alert sirens and rocket fire on a daily basis. We investigated whether the exposure to these stressful circumstances, which peaked during three large military operations (MO), was associated with increased glucose levels among the civilian population. We included all fasting serum glucose tests taken between 2007–2014, of Clalit Health Services members in Southern Israel who had at least one fasting glucose test during an MO period and at least one test drawn at other times. We analyzed the association between MO periods and glucose using linear mixed-effects models. We included 408,706 glucose tests (10% during MO periods). Among subjects who reside in proximity to Gaza, glucose levels were 2.10% (95% CI 1.24%; 2.97%) higher in MO days compared to other times. A weaker effect was observed among subjects in more remote locations. In conclusion, we found stress to be associated with increased fasting glucose levels, especially among those who reside in locations in which the intensity of the threat is higher. Since glucose may be a marker of the population at cardiovascular risk, further studies are required. |
format | Online Article Text |
id | pubmed-6997375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-69973752020-02-10 The association between an increase in glucose levels and armed conflict-related stress: A population-based study Yitshak-Sade, Maayan Mendelson, Nitsan Novack, Victor Codish, Shlomi Liberty, Idit F. Sci Rep Article Studies have shown stress may lead to diabetes-related morbidities. In recent years during enhanced hostility periods, the population of Southern Israel experienced alert sirens and rocket fire on a daily basis. We investigated whether the exposure to these stressful circumstances, which peaked during three large military operations (MO), was associated with increased glucose levels among the civilian population. We included all fasting serum glucose tests taken between 2007–2014, of Clalit Health Services members in Southern Israel who had at least one fasting glucose test during an MO period and at least one test drawn at other times. We analyzed the association between MO periods and glucose using linear mixed-effects models. We included 408,706 glucose tests (10% during MO periods). Among subjects who reside in proximity to Gaza, glucose levels were 2.10% (95% CI 1.24%; 2.97%) higher in MO days compared to other times. A weaker effect was observed among subjects in more remote locations. In conclusion, we found stress to be associated with increased fasting glucose levels, especially among those who reside in locations in which the intensity of the threat is higher. Since glucose may be a marker of the population at cardiovascular risk, further studies are required. Nature Publishing Group UK 2020-02-03 /pmc/articles/PMC6997375/ /pubmed/32015387 http://dx.doi.org/10.1038/s41598-020-58679-z Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Yitshak-Sade, Maayan Mendelson, Nitsan Novack, Victor Codish, Shlomi Liberty, Idit F. The association between an increase in glucose levels and armed conflict-related stress: A population-based study |
title | The association between an increase in glucose levels and armed conflict-related stress: A population-based study |
title_full | The association between an increase in glucose levels and armed conflict-related stress: A population-based study |
title_fullStr | The association between an increase in glucose levels and armed conflict-related stress: A population-based study |
title_full_unstemmed | The association between an increase in glucose levels and armed conflict-related stress: A population-based study |
title_short | The association between an increase in glucose levels and armed conflict-related stress: A population-based study |
title_sort | association between an increase in glucose levels and armed conflict-related stress: a population-based study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997375/ https://www.ncbi.nlm.nih.gov/pubmed/32015387 http://dx.doi.org/10.1038/s41598-020-58679-z |
work_keys_str_mv | AT yitshaksademaayan theassociationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT mendelsonnitsan theassociationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT novackvictor theassociationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT codishshlomi theassociationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT libertyiditf theassociationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT yitshaksademaayan associationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT mendelsonnitsan associationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT novackvictor associationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT codishshlomi associationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy AT libertyiditf associationbetweenanincreaseinglucoselevelsandarmedconflictrelatedstressapopulationbasedstudy |