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Negatively charged amino acids at the foot-and-mouth disease virus capsid reduce the virion-destabilizing effect of viral RNA at acidic pH
Elucidation of the molecular basis of the stability of foot-and-mouth disease virus (FMDV) particles is relevant to understand key aspects of the virus cycle. Residue N17D in VP1, located at the capsid inner surface, modulates the resistance of FMDV virion to dissociation and inactivation at acidic...
Autores principales: | Caridi, Flavia, López-Argüello, Silvia, Rodríguez-Huete, Alicia, Torres, Elisa, Bustos, María J., Cañas-Arranz, Rodrigo, Martín-Acebes, Miguel A., Mateu, Mauricio G., Sobrino, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997383/ https://www.ncbi.nlm.nih.gov/pubmed/32015411 http://dx.doi.org/10.1038/s41598-020-58414-8 |
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