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Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome
BACKGROUND: The ovulatory dysfunction mechanisms underlying polycystic ovary syndrome (PCOS) are not completely understood. There is no effective therapy for PCOS so far. METHODS: We measured the expression of four and a half LIM domain 2 (FHL2) and other related-genes in human granulosa cells (hGCs...
Autores principales: | Zhou, Ruiqiong, Li, Shang, Liu, Jiansheng, Wu, Hasiximuke, Yao, Guangxin, Sun, Yun, Chen, Zi-Jiang, Li, Weiping, Du, Yanzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997507/ https://www.ncbi.nlm.nih.gov/pubmed/32028069 http://dx.doi.org/10.1016/j.ebiom.2020.102635 |
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