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The Stereoselective Nitro-Mannich Reaction in the Synthesis of Active Pharmaceutical Ingredients and Other Biologically Active Compounds

The nitro-Mannich (aza-Henry) reaction, in which a nitroalkane and an imine react to form a β-nitroamine, is a versatile tool for target-oriented synthesis. Although the first stereoselective reaction was developed only 20 years ago, and enantioselective and diastereoselective versions for the synth...

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Detalles Bibliográficos
Autores principales:	Faisca Phillips, Ana Maria, Guedes da Silva, M. Fátima C., Pombeiro, Armando J. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997535/ https://www.ncbi.nlm.nih.gov/pubmed/32047742 http://dx.doi.org/10.3389/fchem.2020.00030

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