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Down-regulation of argininosuccinate lyase induces hepatoma cell apoptosis through activating Bax signaling pathway

Argininosuccinate lyase (ASL) plays an important role in the hepatic urea cycle, and can catalyze the reversible reaction of argininosuccinate to arginine and fumarate. However, the function of ASL in hepatocellular carcinoma (HCC) is not fully understood. In this study, we found that ASL expression...

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Detalles Bibliográficos
Autores principales: Gong, Rui, He, Lin, Zhou, HongZhong, Cheng, ShengTao, Ren, Fang, Chen, Juan, Ren, JiHua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997574/
https://www.ncbi.nlm.nih.gov/pubmed/32042869
http://dx.doi.org/10.1016/j.gendis.2018.11.003