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Down-regulation of argininosuccinate lyase induces hepatoma cell apoptosis through activating Bax signaling pathway
Argininosuccinate lyase (ASL) plays an important role in the hepatic urea cycle, and can catalyze the reversible reaction of argininosuccinate to arginine and fumarate. However, the function of ASL in hepatocellular carcinoma (HCC) is not fully understood. In this study, we found that ASL expression...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Chongqing Medical University
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997574/ https://www.ncbi.nlm.nih.gov/pubmed/32042869 http://dx.doi.org/10.1016/j.gendis.2018.11.003 |